There are many textbooks on the design and analysis of experiments. This is just a selection of some of them. It includes several classical texts, some of which are still available. Many statistical textbooks also devote some pages to experimental design.
Books about experimental design
Altman,D.G. (1991): Practical statistics for medical research. Chapman and Hall, London, Glasgow, New York.
Cox DR, Reid N. The theory of the design of experiments. Boca Raton, Florida: Chapman and Hall/CRC Press, 2000.
Howell,D.C. (1999): Fundamental Statistics for the Behavioral Sciences. Duxbury Press, PacificGrove, London, New York.
Montgomery,D.C. (1997): Design and analysis of experiments. Wiley, New York.
Books on the R statistical package
There are many new books on the R statistical package. Here are three which are useful for beginners
Crawley MJ. Statistics. An introduction using R. 1st ed. Chichester: John Wiley & Sons, Ltd, 2005
Ekstrom CT. The R Primer. 2011. CRC Press. ISBN 978-1-4398-6206-3